| Cost | Published Range or Example |
|---|---|
| Initial consultation | ¥0–¥50,000 |
| Median consultation fee | ¥5,500 |
| Average consultation fee | ¥14,000 |
| Testing examples | ¥22,000–¥77,000 |
| Stem cell treatment examples | About ¥2.01 million–¥4.95 million |
Tokyo Consultation Fees: ¥0–¥50,000
| Clinic | Initial Consultation Fee | Other Published Cost Information |
|---|---|---|
| Bioregen Clinic | ¥0 | Infectious disease test: ¥22,000. Overseas patients may use international medical pricing.[1] |
| Clinic Le GINZA | ¥3,500 including tax | Follow-up regenerative medicine consultation: ¥2,000 including tax.[2] |
| Saisei no Mori Clinic Roppongi | ¥5,500 | Knee osteoarthritis adipose-derived stem cell treatment: from about ¥2.01 million including tax.[3] |
| Tokyo RELIFE Clinic | ¥11,000 including tax | Separate prices are published for testing, treatment, and cell storage.[4] |
| Sunfield Clinic | ¥50,000 before consumption tax | Published stem cell treatment fee: ¥2.95 million before tax.[5] |
Five-Clinic Price Snapshot
| Measure | Result |
|---|---|
| Lowest listed consultation fee | ¥0 |
| Lowest paid consultation fee | ¥3,500 |
| Highest listed consultation fee | ¥50,000 before tax |
| Median | ¥5,500 |
| Arithmetic average | ¥14,000 |
| Consultation fees between ¥3,500 and ¥11,000 | 3 of 5 clinics |
| Highest paid fee vs. lowest paid fee | About 14.3× |
The five prices are spread unevenly. The ¥50,000 fee pulls the arithmetic average up to ¥14,000, while the middle value is ¥5,500. In a sample this small, the median gives a clearer view of where most of the listed consultation prices sit.
Consultation Cost vs. Treatment Cost
| Clinic | Consultation | Published Treatment Example | Consultation as Share of Treatment Price |
|---|---|---|---|
| Saisei no Mori Clinic Roppongi | ¥5,500 | About ¥2.01 million | About 0.3% |
| Tokyo RELIFE Clinic | ¥11,000 | ¥2.2 million knee treatment | 0.5% |
| Sunfield Clinic | ¥50,000 before tax | ¥2.95 million before tax | About 1.7% |
In these same-clinic examples, the consultation accounts for only about 0.3% to 1.7% of the published treatment price.
A ¥3,500 consultation and a ¥50,000 consultation differ by ¥46,500. The gap between the ¥2.01 million and ¥4.95 million treatment examples is about ¥2.94 million. That treatment-price difference is about 63 times larger.
First-Visit Add-On Costs: ¥22,000–¥77,000
| Item | Published Price |
|---|---|
| Bioregen infectious disease blood test | ¥22,000[1] |
| Tokyo RELIFE basic examination set | ¥44,000 including tax[4] |
| Tokyo RELIFE comprehensive diagnostic package | ¥59,400 including tax[4] |
| Tokyo RELIFE pre-operation testing | ¥77,000 including tax[4] |
The highest and lowest examples differ by ¥55,000. They are not interchangeable packages, so the useful comparison is not the price alone but the exact tests included.
- Ask whether recent blood tests from another hospital are accepted.
- Ask how recent MRI, CT, or X-ray images must be.
- Ask whether infection screening is required before tissue collection.
- Ask whether ECG or other pre-procedure tests are required.
Published Treatment Prices: ¥2.01M–¥4.95M
| Clinic and Treatment Example | Published Price |
|---|---|
| Saisei no Mori Clinic Roppongi — knee osteoarthritis adipose-derived stem cell treatment | From about ¥2.01 million including tax[3] |
| Tokyo RELIFE — knee osteoarthritis stem cell therapy | ¥2.2 million including tax[4] |
| Tokyo RELIFE — 100 million cells | ¥2.75 million including tax[4] |
| Sunfield Clinic — listed stem cell treatment | ¥2.95 million before tax[5] |
| Bioregen Clinic — adipose-derived stem cell drip | ¥3.52 million including tax[1] |
| Tokyo RELIFE — 200 million cells | ¥4.95 million including tax[4] |
- Lowest example: about ¥2.01 million.
- Highest example: ¥4.95 million.
- Difference: about ¥2.94 million.
- Highest price is about 2.46× the lowest.
- Four of the six examples are below ¥3 million.
These six figures cover different conditions, cell numbers, treatment routes, and protocols, so they should not be read as a Tokyo average.
A useful comparison starts with the treatment itself, not the headline price: stem cell treatment costs in Japan.
¥2,948,000 Budget Example
| Tokyo RELIFE Published Item | Price | Share of Example Subtotal |
|---|---|---|
| Initial consultation | ¥11,000 | About 0.4% |
| Pre-operation testing | ¥77,000 | About 2.6% |
| 100-million-cell treatment | ¥2,750,000 | About 93.3% |
| Annual cell storage | ¥110,000 | About 3.7% |
| Subtotal | ¥2,948,000 | 100% |
This calculation combines separately published prices and is not a standard treatment plan. More than 93% of the example subtotal comes from the treatment itself. The initial consultation accounts for less than 0.4%.
Cell Number: ¥2.75M vs. ¥4.95M
| Tokyo RELIFE Published Cell Number | Price |
|---|---|
| 100 million cells | ¥2.75 million |
| 200 million cells | ¥4.95 million |
Doubling the listed cell number raises the price by ¥2.2 million, or about 80%.[4]
- Ask why that cell number is being recommended.
- Ask whether published human studies used a similar dose.
- Ask whether the studies used the same administration route.
- Do not assume that a larger cell number automatically means a better result.
Cell Storage: ¥110,000 per Year Example
Tokyo RELIFE lists annual cell storage at ¥110,000 for some therapies.[4]
| Simple Projection | Cost if Annual Price Stayed at ¥110,000 |
|---|---|
| 1 year | ¥110,000 |
| 3 years | ¥330,000 |
| 5 years | ¥550,000 |
The projection uses simple arithmetic only. It does not assume that future storage prices will remain unchanged.
- What exactly is being stored?
- How long can it be stored?
- Is future treatment charged separately?
- What happens if storage is cancelled?
Repeat Sessions Can Multiply the Bill
| Illustrative Price per Session | Number of Sessions | Arithmetic Total |
|---|---|---|
| ¥2.5 million | 1 | ¥2.5 million |
| ¥2.5 million | 2 | ¥5 million |
| ¥2.5 million | 3 | ¥7.5 million |
This is a cost calculation only. It does not say whether one, two, or three sessions are medically appropriate.
Get the number of planned sessions in writing before paying.
What the Consultation Must Give You
- Exact diagnosis or condition being treated
- Exact cells or biological material being proposed
- Cell source
- Administration route
- Cell number or dose, where relevant
- Number of planned sessions
- Required testing
- Evidence for your condition
- Main procedure-specific risks
- Standard treatment alternatives
- Expected total medical cost
- Expected treatment timeline
Free Consultation: Check These Five Points
Bioregen Clinic lists ¥0 for its initial and follow-up consultation fees for the listed stem cell therapy.[1]
- Will you speak directly with a physician?
- Will the physician review your medical records?
- Is another paid physician assessment required later?
- Are blood tests or imaging charged separately?
- Does international-patient pricing apply?
Bioregen states that overseas patients are generally handled through medical coordination and that international medical pricing applies.[1]
Overseas Patients: Check Costs Before Buying Flights
- Can a physician review records before travel?
- Can the first consultation be remote?
- Are overseas MRI, CT, X-rays, and laboratory results accepted?
- How recent must the records be?
- How many separate visits are required?
- How long does cell preparation take?
- Can follow-up be done remotely?
- Are interpretation and translation included?
- Is medical coordination billed separately?
- Does the Japanese website price apply to overseas patients?
Sunfield Clinic’s published schedule describes roughly eight weeks between fat collection and stem cell administration for certain autologous adipose-derived mesenchymal stem cell procedures.[5]
Flights, accommodation, local transport, meals, companion costs, and time away from work sit outside the clinic’s medical price.
See also: medical travel guide for stem cell treatment in Japan.
Stem Cells and Exosomes Are Not the Same Treatment
| Question | What You Need to Know |
|---|---|
| What is administered? | Living cells, culture supernatant, extracellular vesicles, exosome-related material, or something else |
| Does it contain living cells? | Yes or no |
| What is the source? | Patient-derived, donor-derived, or another source |
| How is it administered? | Joint injection, intravenous infusion, local injection, or another route |
An exosome-related price and a living-cell treatment price should not be treated as two prices for the same procedure.
Japanese Regulatory Status: Check the Exact Route
Japan’s amended regenerative medicine law took effect on May 31, 2025.[6]
| Term | What to Check |
|---|---|
| Regenerative medicine provision plan | Exact treatment name and plan information |
| Certified regenerative medicine committee | Which committee reviewed the relevant plan |
| Cell-processing facility | Where the cells are processed |
| PMDA-authorized regenerative medical product | Exact named product and approved indication |
A regenerative medicine provision plan is not the same thing as PMDA marketing authorization for a named regenerative medical product.[7][8]
Regulatory status alone does not show that a treatment will work for a particular disease.
See also: Japan regenerative medicine registration and compliance.
Evidence: Match These Seven Items
- Same or closely related medical condition
- Same cell type
- Similar cell preparation
- Similar dose or cell number
- Same administration route
- Meaningful comparison group
- Long enough follow-up
A knee-injection study does not establish effectiveness for an unrelated neurological, cardiovascular, liver, kidney, or autoimmune condition.
The International Society for Stem Cell Research recommends checking scientific evidence, safety, regulatory status, and available alternatives when evaluating stem cell interventions.[10]
Safety: Ask About the Exact Procedure
| Stage | Examples of Issues to Ask About |
|---|---|
| Tissue collection | Pain, bleeding, bruising, infection, anesthesia, recovery |
| Cell processing | Processing method, testing, storage, release criteria |
| Joint or local injection | Local complications related to the treatment site |
| Intravenous administration | Procedure-specific systemic risks, including embolic risk |
Japan’s Ministry of Health, Labour and Welfare has circulated safety guidance concerning intravenous administration of mesenchymal stem cells, including attention to embolic risk.[9]
“Autologous” means the cells come from the patient. It does not make collection, processing, or administration risk-free.
See also: stem cell therapy safety in Japan.
Written Quote Checklist
| Cost Item | Confirm in Writing |
|---|---|
| Initial physician consultation | Included / separate |
| Follow-up consultations | Number included |
| Blood tests | Exact tests and price |
| Infectious disease screening | Included / separate |
| Imaging | Existing scans accepted? |
| Tissue collection | Included / separate |
| Anesthesia and medication | Included / separate |
| Cell processing and culture | Included / separate |
| Quality testing | Included / separate |
| Administration | Per session or complete course? |
| Repeat sessions | Exact number planned |
| Cell storage | Annual or multi-year price |
| Follow-up | Duration and number of visits |
| Interpretation | Included / separate |
| International coordination | Included / separate |
| Consumption tax | Included / added later |
| Cancellation and refund | Exact non-refundable stages |
The quote should also state the exact treatment, cell source, dose or cell number, administration route, treatment area, and number of sessions.
Refund and Cancellation Questions
- When does the consultation fee become non-refundable?
- When do testing charges become non-refundable?
- What happens after tissue collection has started?
- What happens after cell processing has started?
- What happens if processing cannot be completed?
- What happens if the doctor later decides not to proceed?
- What happens if your health changes before treatment?
- What happens if treatment is completed but you do not improve?
Do Not Pay a Large Deposit Yet If
- You do not have a clear diagnosis.
- You do not know exactly what will be administered.
- You do not know the cell source.
- You do not know the administration route.
- You do not know how many sessions are planned.
- The clinic will not give you a complete written price.
- The supporting evidence does not match your condition.
- Regulatory status is presented as proof of effectiveness.
- A success percentage is given without explaining how success was measured.
- Refund conditions are unclear.
- You are being pressured to pay before receiving a clear treatment plan.
Clinic Comparison Sheet
| Item | Clinic A | Clinic B | Clinic C |
|---|---|---|---|
| Consultation fee | |||
| Exact treatment | |||
| Cell source | |||
| Cell number or dose | |||
| Administration route | |||
| Treatment areas | |||
| Number of sessions | |||
| Tests included | |||
| Collection included | |||
| Processing included | |||
| Storage fee | |||
| Follow-up included | |||
| Tax included | |||
| Total expected cost | |||
| Refund terms |
Finally
For the five Tokyo clinics reviewed, published consultation fees run from ¥0 to ¥50,000, and the median is ¥5,500. The six treatment examples range from about ¥2.01 million to ¥4.95 million. In the three same-clinic comparisons above, the consultation is only about 0.3% to 1.7% of the treatment price. The Tokyo RELIFE calculation reaches ¥2,948,000 once consultation, pre-operation testing, a 100-million-cell treatment, and one year of storage are combined. The practical comparison is the full treatment bill: sessions, tests, processing, storage, tax, follow-up, and refund terms.
Sources
- Bioregen Clinic. Official price list covering consultation, stem cell therapy, infectious disease testing, and overseas-patient pricing. Bioregen Clinic Price List
- Clinic Le GINZA. Official consultation flow and regenerative medicine consultation fees. Clinic Le GINZA Consultation Information
- Saisei no Mori Clinic Roppongi. Official regenerative medicine menu and published fees. Saisei no Mori Clinic Menu and Fees
- Tokyo RELIFE Clinic. Official prices for consultation, testing, stem cell therapy, and cell storage. Tokyo RELIFE Clinic Price List
- Sunfield Clinic. Official stem cell therapy information covering published fees and treatment timing. Sunfield Clinic Stem Cell Therapy
- Ministry of Health, Labour and Welfare. Information concerning amendments to Japan’s regenerative medicine legislation. MHLW Regenerative Medicine Law Information
- Ministry of Health, Labour and Welfare. Procedures for regenerative medicine provision plans. MHLW Regenerative Medicine Provision Plans
- Pharmaceuticals and Medical Devices Agency. Approved regenerative medical products in Japan. PMDA Approved Regenerative Medical Products
- Ministry of Health, Labour and Welfare. Safety information concerning intravenous administration of mesenchymal stem cells. MHLW Safety Information
- International Society for Stem Cell Research. Patient guidance for evaluating stem cell treatments. ISSCR Guide to Stem Cell Treatments
Medical note: This page provides general information. Diagnosis, eligibility, risks, treatment choice, and alternatives require an individual medical assessment.
Price note: Prices and policies were checked against publicly available information in August 2026 and can change. Get a current written quotation before paying a deposit or arranging travel.