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PERIODONTITIS TREATMENT

Periodontitis Treatment

Adipose-derived stem cells support alveolar bone repair, gum tissue regeneration and oral-systemic health.

  • Alveolar Bone Repair
  • Gum Regeneration
  • Systemic Health
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Beyond Surface Cleaning

Periodontal Disease Is a Systemic Risk, Not Just a Local Issue

Periodontitis is driven by bacterial infection and chronic inflammation at the gum-tooth interface. If left untreated, it progressively destroys the alveolar bone, leading to tooth loosening and loss. More importantly, periodontal inflammation and bacterial by-products enter the bloodstream, worsening blood glucose control, accelerating atherosclerosis and increasing the risk of myocardial infarction and stroke. Stem-cell injection at the periodontal pocket supports bone regeneration, controls inflammation and contributes to overall systemic health.

Why Periodontal Care Matters Beyond the Mouth

A deeper, more considered approach

  • Inflammatory mediators enter the bloodstream and impair insulin sensitivity.
  • Periodontal bacteria contribute to plaque formation in arteries, narrowing blood flow.
  • Patients with periodontitis have approximately 2.8 times higher risk of cerebral infarction.
  • Diabetes and periodontitis form a two-way worsening cycle.
  • Alveolar bone loss is irreversible once it progresses past a clinical threshold.

Targeted Repair

Why Stem-Cell Therapy Can Regenerate the Periodontal Foundation

01

Local Alveolar Bone Repair

Adipose-derived MSCs delivered into the periodontal pocket differentiate toward bone-lineage cells, supporting alveolar bone regrowth.
02

Anti-Inflammatory Action

Stem cells suppress local cytokine storms, reducing gum bleeding, swelling and progressive tissue destruction.
03

Neovascularization

New micro-vessel formation restores blood supply to damaged periodontal tissue.
04

Differentiation Toward Periodontal Cells

MSCs can differentiate into periodontal ligament, cementum and bone-related cells.
05

Whole-Body Metabolic Benefit

Reduced oral inflammation improves glucose control and lowers vascular risk factors.
06

Compatible with Systemic Stem-Cell Care

Local periodontal treatment can be combined with systemic stem-cell IV reinfusion for integrated care.

Clinical Improvements

Improvements Patients May Experience

  • Reduced gum bleeding and swelling within weeks
  • Stabilization of loose teeth and improved biting comfort
  • Visible bone-fill on follow-up imaging
  • Better fasting glucose in patients with co-existing diabetes
  • Reduced risk markers linked to atherosclerosis and stroke

Suitable Candidates

Designed for individual needs

  • Adults with moderate to severe periodontitis and progressive bone loss
  • Patients with diabetes affected by gum inflammation
  • Those seeking to avoid extractions and preserve natural teeth
  • Patients with cardiovascular risk concerned about oral-systemic link
  • Those who have not responded to conventional periodontal therapy

Patient Stories

Observed changes and clinical stories

Periodontitis — Long-Standing Case

After adipose-derived stem-cell injection into the periodontal pocket, bleeding on probing and bone loss were both reported to be stabilized at six-month follow-up.

Combined Systemic & Local Care

A middle-aged patient received periodontal MSC injection alongside systemic stem-cell IV reinfusion. Self-reported discomfort and gingival index both improved.

Private, professional, precise

Safety, Serenity, Reassurance — Your Triple Assurance

GINZA CLINIC is equipped with a Japanese medical-grade CPC laboratory. Consultation, collection, culture and reinfusion follow independent, standardized and stringent aseptic processes. One-to-one physician-led care protects privacy, peace of mind and efficiency.