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CHRONIC PAIN

Chronic Pain

Stem-cell therapy modulates inflammation, supports tissue repair and helps break the chronic pain cycle.

  • Inflammation Modulation
  • Tissue Repair
  • Lasting Relief
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Beyond Painkillers

Chronic Pain Deserves Source-Level, Not Symptom-Level, Care

When pain persists for more than 3-6 months after the original injury or disease has healed, it is classified as chronic pain. Conventional treatment—medication, physical therapy, nerve blocks—often fails to deliver lasting relief and may carry long-term side effects. Stem-cell therapy offers a regenerative alternative: autologous MSCs seek damaged tissue via homing signals, reduce local inflammation and gradually restore microenvironmental balance.

Why Chronic Pain Is So Hard to Resolve

A deeper, more considered approach

  • Pain-sensing neurons and glial cells develop abnormal firing patterns.
  • Persistent inflammatory cytokines maintain nociceptive sensitization.
  • Long-term medication can produce tolerance and side effects.
  • Chronic pain damages sleep, mood and social participation.
  • Pain cycle — pain, anxiety, sleep loss, more pain — is self-reinforcing.

Source-Level Care

Why Stem-Cell Therapy Is a Real Option for Refractory Chronic Pain

01

Targeted Homing Effect

MSCs respond to damage signals and migrate precisely to inflamed or injured tissue.
02

Anti-Inflammatory Modulation

Stem cells suppress pro-inflammatory cytokines that sustain chronic pain.
03

Neural Environment Repair

MSCs help restore normal neuron-glia signaling, reducing pathologic sensitization.
04

Tissue Regeneration Support

Local repair of micro-damage reduces the original source of pain signals.
05

Immune Rebalancing

MSCs rebalance immune responses, supporting systemic recovery from chronic inflammation.
06

Autologous, Low Side-Effect Profile

Using the patient’s own cells minimizes immune risk and treatment burden.

Recovery Indicators

Improvements Patients May Experience

  • Reduced pain scores on VAS/NRS scales within weeks
  • Improved sleep quality and reduced nighttime awakening
  • Lower reliance on painkillers and anti-inflammatory drugs
  • Improved mobility, mood and social participation
  • Reduced systemic inflammatory markers in blood tests

Suitable Candidates

Designed for individual needs

  • Patients with chronic musculoskeletal pain unresponsive to standard therapy
  • Patients with chronic shoulder, knee or spinal joint pain
  • Patients with neuropathic pain or post-surgical persistent pain
  • Patients with chronic headaches or fibromyalgia-type syndromes
  • Those seeking to reduce long-term medication and improve quality of life

Patient Stories

Observed changes and clinical stories

Long-Standing Shoulder Pain

A 30-something patient with several years of persistent right shoulder pain received MSC infusion and reported meaningful pain reduction and range-of-motion gains.

Mixed-Source Pain with Multiple Joints

A 50-year-old patient with knee and shoulder pain from long-term karate training responded well to MSC therapy, returning to daily activities with reduced discomfort.

Private, professional, precise

Safety, Serenity, Reassurance — Your Triple Assurance

GINZA CLINIC is equipped with a Japanese medical-grade CPC laboratory. Consultation, collection, culture and reinfusion follow independent, standardized and stringent aseptic processes. One-to-one physician-led care protects privacy, peace of mind and efficiency.