Japan Medical
Tokyo, Japan International Patient Support
Contact Us

LIVER & KIDNEY DYSFUNCTION

Liver and Kidney Dysfunction

Stem-cell therapy supports hepatocyte regeneration, anti-fibrotic action and renal microenvironment improvement.

  • Hepatic Repair
  • Anti-Fibrosis
  • Renal Support
SCROLL

Organ-Level Repair

Address Liver & Kidney Decline at the Cellular Source

The liver performs more than 500 vital functions—from detoxification and metabolism to immune regulation. Once fibrosis progresses, it is generally considered irreversible, leaving liver transplantation as the only curative option. Similarly, chronic kidney disease progresses silently toward renal failure. Stem-cell therapy aims to regenerate hepatocytes, dissolve early fibrosis, modulate renal inflammation and restore the microenvironment of both organs.

Why Conventional Therapy Often Cannot Reverse Damage

A deeper, more considered approach

  • Antiviral drugs control virus but do not restore hepatocytes.
  • Anti-fibrotic drugs are limited and slow-acting.
  • Liver transplantation has donor shortages and lifelong immune risk.
  • Kidney disease progresses silently until late-stage renal failure.
  • Standard medications carry long-term side effects.

Hepatorenal Repair Standard

Why Stem-Cell Therapy Represents a New Standard for Liver & Kidney Care

01

Hepatocyte Regeneration

MSCs differentiate toward hepatocyte-like cells and stimulate proliferation of residual liver cells.
02

Anti-Fibrotic Action

Stem cells secrete MMPs and anti-fibrotic cytokines that help dissolve early-stage fibrosis.
03

Immune Regulation for Hepatitis

In autoimmune hepatitis, MSCs rebalance overactive immune responses.
04

Renal Microenvironment Repair

Stem cells support glomerular and tubular cell survival, slowing CKD progression.
05

Detox & Metabolic Support

Improved hepatic function restores detoxification, energy metabolism and lipid balance.
06

Autologous, Low-Risk Source

Treatment uses the patient’s own adipose-derived stem cells, avoiding immune rejection and tumor risk.

Recovery Indicators

Improvements Patients May Experience

  • Improved AST, ALT and γ-GTP values in follow-up testing
  • Reduced fatigue and easier physical activity
  • Improved appetite, digestion and alcohol tolerance
  • Stabilized eGFR and reduced proteinuria for early-stage CKD
  • Lowered risk of progressing to cirrhosis or liver cancer

Suitable Candidates

Designed for individual needs

  • Patients with chronic hepatitis B/C and progressive fibrosis
  • Patients with mild to moderate cirrhosis awaiting transplantation
  • Patients with non-alcoholic fatty liver disease (NAFLD/NASH)
  • Patients with early to mid-stage chronic kidney disease
  • Those seeking to avoid long-term medication and its side effects

Patient Stories

Observed changes and clinical stories

Liver Fibrosis Stabilization

After serial adipose-derived MSC infusions, a patient with chronic hepatitis B showed stabilized fibrosis markers and improved energy levels.

Early-Stage CKD Support

A patient with stage 2-3 CKD received MSC therapy. eGFR trend stabilized and reported fatigue improved within months.

Private, professional, precise

Safety, Serenity, Reassurance — Your Triple Assurance

GINZA CLINIC is equipped with a Japanese medical-grade CPC laboratory. Consultation, collection, culture and reinfusion follow independent, standardized and stringent aseptic processes. One-to-one physician-led care protects privacy, peace of mind and efficiency.